• Sat. Jan 22nd, 2022

Malabsorption syndrome


Apr 3, 2021
Malabsorption syndrome

MALABSORPTION SYNDROME – a syndrome of impaired intestinal absorption. Clinical syndrome caused by disorders of absorption through the mucous membrane of the small intestine of one or more nutrients. Etiology and pathogenesis. Malabsorption syndrome can be primary (hereditary) or secondary (acquired). Etiology in each case different (absence or reduced activity of lactase, alpha-glucosidase, enterokinase and so on). Among hereditary disturbed intestinal absorption occur disaccharidase deficiency (lactase, saharasia, isomaltase), true celiac disease (intolerance to gliadin), failure enterokinase, intolerance monosaccharides (glucose, fructose, galactose), malabsorption of amino acids (zistinurija, disease Hartnup and others), malabsorption of vitamin B12 and folic acid, and so on, Secondary, or acquired, malabsorption, the companion of many chronic diseases of the stomach and intestines (pancreatitis, hepatitis, intestinal dysbiosis, intestinal infections of dyskinesia, Crohn’s disease and others).

Clinical picture

The clinical picture in children is dominated by chronic diarrhea with a high content of lipids in Calais. Gradually develops dystrophy, children lag behind in growth. Join manifestations of vitamin a deficiency, disorders of water and electrolyte balance (dry skin, eating, glossitis, hypocupremia, hyponatremia, hypocalcemia, and others). Due to the developed gipoproteinemii can be edema. Depending on the cause of impaired intestinal absorption, the disease can develop in the first months of life (for example, in congenital absence of the Lac-basins) or much later, usually when translated into artificial diet (sucrose intolerance) C etc.

Malabsorption syndrome

The diagnosis of impaired intestinal absorption easily be suspected if a long time has frequent liquefied stools with a high content of fat in the stool and almost untreatable by traditional means. The treatment in each case must be strictly etiological. So, intolerance to sucrose exclude from food products containing sucrose, starch (sugar, potatoes, semolina), as well as products made from flour. Over time, tolerance to sucrose increases and diet expands. When lactose in mild cases limited to reducing the number given milk and early introduction of sucrose and starch.


In severe eliminate maternal and cow’s milk and replace it with plant species (soy, almond), appoint protein hydrolysates and other celiac disease exclude grains, widely used enzyme preparations. The main provision which must survive in malabsorption, as close as possible to diagnose the disease before starting treatment, preventing deep metabolic shifts. The prognosis for early diagnosis and treatment is favorable. Prevention is to diet with the exception unbearable products..